=============================================================== == -- ALS INTEREST GROUP -- == == ALS DIGEST (#18, 05 FEB 1993) == == To subscribe, unsubscribe, or to contribute notes, please == == send e-mail to bro@huey.met.fsu.edu (Bob Broedel). == =============================================================== these references are for the article in # 18 E) REFERENCES Albers, G. W., Goldberg, M. P., Choi, D. W. (1989). N-methyl-D- aspartate antagonists: ready for clinical trial in brain ischemia? Annals of neurology, 25, 398-403. Allaoua, H., Chaudieu, I., Krieger, C., Boksa, P., Privat, A., Quirion, R. (1992). Alterations in spinal cord excitatory amino acid receptors in amyotrophic lateral sclerosis patients. Brain research, 579, 169-172. Andersson, T., Schultzberg, M., Schwarcz, R., L ve, A., Wickman, C. and Kristens-son, K. (1991). European journal of neuroscience, 3, 66-71. Aanonsen, L. M., Lei S., Wilcox, G. L. (1990). Excitatory amino acid receptors and nociceptive neurotransmission in rat spinal cord. Pain, 41, 309-321. Arslan, M., Pohl, C. R. and Plant, T. M. (1988). DL-2-amino-5-phosphonopentanoic acid, a specific N-methyl-D-aspartic acid receptor antagonist, suppresses pulsatile LH release in the rat. Neuroendocrinology, 47, 465-468. Bennett, D. A., Lehmann, J., Bernard, P. S., Liebman, J. M., Williams, M., Wood, P. L., Boast, C. A., Hutchison, A. J. (1990). CGS 19755: a novel competitive N-methyl-D- aspartate (NMDA) receptor antagonist with anticonvulstant, anxiolytic and anti- ischemic properties. Current and future trends in anticonvulsant, anxiety, and stroke therapy, 519-524. Bertrand, G., Gross, R., Puech, R., Loubati res-Mariani, M. M., Bockaert, J. (1992). Evidence for a glutamate receptor of the AMPA subtype which mediates insulin release from rat perfused pancreas. British journal of pharmacology, 106, 354-359. Bobbin, R. P. and Ceasar, G. (1987). Kynurenic acid and -D-glutamylamino-methylsulfonic acid suppress the compound action potential of the auditory nerve. Hearing research, 25, 77-81. Bullock, R. Graham, D. I., Chen, M.-H., Lowe, D., McCulloch, J. (1990). Focal cerebral ischemia in the cat: pretreatment with a competitive NMDA receptor antagonist, D- CPP-ene. Journal of cerebral blood flow nd metabolism, 10, 668-674. Brann, D. W., Mahesh, V. B. (1991). Endogenous excitatory amino acid regulation of the progesterone-induced LH and FSH surge in estrogen-primed ovariectomized rats. Neuroendocrinology, 53, 107-110. Carlsson, M., Carlsson, A. (1990). Interactions between glutamatergic and monoami-nergic systems within the basal ganglia - implications for schizophrenia and Parkinson's disease. Trends in neurosciences, 13, 272-276. Cherubini, E., Herrling, P. L., Lanfumey, L. and Stanzione, P. (1988). Excitatory amino acids in synaptic excitation of rat striatal neurones in vitro. Journal of physiology, 400, 677-690. Choi, D. W. (1990). The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death. Annual revue of neuroscience, 13, 171-182. Davies, J., Evans, R. H., Herrling, P. L., Jones, A. W., Olverman, H. J., Pook, P. and Watkins, J. C. (1986). CPP, a new potent and selective NMDA antagonist. Depression of central neuron responses, affinity for [3H]D-AP5 binding sites on brain membranes and anticonvulsant activity. Brain research, 382, 169-173. Davies, J. (1988). A reappraisal of the role of NMDA and non-NMDA receptors in neurotransmission in the cat dorsal horn. In Frontiers in excitatory amino acid research (eds. E. Cavalheiro, J. Lehmann, L. Turski) A.R.Liss, New York, pp. 355-362. Davies, S. N. and Lodge, D. (1987). Evidence for involvement of N-methylaspartate receptors in 'wind-up' of class 2 neurones in the dorsal horn of the rat. Brain research, 424, 402-406. Delay, J., Deniker, P. and Havl, J. M. (1952). Utilisation th rapeutique psychiatrique d'une ph nothiazine d'action centrale s lective. Annales m dicales psychologiques, 110, 112-117. Duncan, M. W., Marini A. M., Watters, R., Kopin I. J, Markey, S. P. (1992). Zinc, a neurotoxin to cultured neurons, contaminates cycad flour prepared by traditional guamanian methods. The journal of neuroscience, 1523-1537. Dunn, R. W., Corbett, R., Martin, L. L., Payack, J. F., Laws-Ricker, R., Wilmot, C. A., Rush, D. K., Cornfeldt, M. L., Fielding, S. (1990). Preclinical anxiolytic profiles of 7189 and 8319, novel non-competitive NMDA antagonists. Current and future trends in anticonvulsant, anxiety, and stroke therapy, 495-512. Eaton, S. A. and Salt, T. E. (1987). N-Methyl-D-aspartate antagonists reduce the responses of rat thalamic neurones to noxious stimulation. Journal of physiology, (London), 394, 114P. Ehrenberger, K. and Brix, R. (1983). Glutamic acid and glutamic acid diethylester in tinnitus treatment. Acta otolaryngol, 95, 599-605. Emmett, M. R., Mick, S. J., Cler, J. A., Rao, T. S., Iyengar, S., Wood, P. L. (1991). Actions of D-cycloserine at the N-methyl-D-aspartate-associated glycine receptor site in vivo. Neuropharmacology, 30, 1167-1171. Erdoe, S. L. (1991). Excitatory amino acid receptors in the mammalian periphery. Trends in pharmacological sciences, 12, 426-429. Estienne, M. J., Schillo, K.K., Hileman, S. M., Green, M. A., Hayes, S. H. (1990a). Effect of N-methyl-D,L-aspartate on luteinizing hormone secretion in ovariectomized ewes in the absence and presence of estradiol. Biology of reproduction, 42, 126-130. Estienne, M. J., Schillo, K. K., Green, M. A., Hileman, S. M. (1990b). Growth hormone release after N-methyl-D,L-aspartate in sheep: dose response and effect of an opioid antagonist. Journal of animal sciences, 68, 3198-3203. Faden, A. I., Ellison, J. A., Noble, L. J. (1990). Effects of competitive and non-competitive NMDA receptor antagonists in spinal cord injury. European journal of pharmacology, 175, 165-174. Farah, J. M., Rao, T. S., Mick, S. J., Coyne, K. E., Iyengar, S. (1991). N-methyl-D-aspartate treatment increases circulating adrenocorticotropin and luteinizing hormone in the rat. Endocrinology, 128, 1875-1880. Ferrari, M. D., Odink, J., Bos, K. D., Malessy, M. J. A., Bruyn, G. W. (1990). Neuroexcitatory plasma amino acids are elevated in migraine. Neurology, 40, 1582-1586. France, C. P., Wood, J. H. and Ornstein, P. (1989). The competitive N-methyl-D-aspartate (NMDA) antagonist CGS 19755 attenuates the rate-decreasing effects of NMDA in rhesus monkeys without producing ketamine-like discriminative stimulus effects. European journal of pharmacology, 159, 133-139. Freed, W.J. (1988). The therapeutic latency of neuroleptic drugs and nonspecific postjunctional supersensitivity. Schizophrenia bulletin, 14, 269-277. Freese, A., Swartz, K. J., During, M. J., Martin, J. B. (1990). Kynurenine metabolites of trypthophan: implications for neurologic diseases. Neurology, 40, 691-695. Fuxe, K., Roberts, P. and Schwarcz, R. (1983). Excitotoxins. MacMillan Press, London. Glavin,G.B., Pinsky,C. and Bose,R. (1989). Mussel poisoning and excitatory amino acid receptors. Trends in pharmaceutical sciences, 10, 15-16. Glavin, G. B., Pinsky, C., Bose, R. (1990). Domoic acid-induced neurovisceral toxic syndrome: characterization of an animal model and putative antidotes. Brain research bulletin, 24, 701-703. Gotti. B., Duverger, D., Bertin, J., Carter, C., Dupont, R., Frost, J., Gaudilliere, B., MacKenzie, E., Rousseau, J., Scatton, B. and Wick, A. (1988). Ifendopril and SL 82.0715 as cerebral anti-ischemic agents. I. Evidence for efficacy in models of focal cerebral ischemia. Journal of pharmaceutical experimental therapeutics, 247, 1211-1221. Greenamyre, J. T. (1986). The role of glutamate in neurotransmission and in neurologic disease. Archives of neurology, 43, 1058-1063. Greenamyre, J. T. and O'Brien, C. F. (1991). N-methyl-D-aspartate antagonists in the treatment of Parkinson's disease. Archives of neurology, 48, 977-981. Gribkoff, V. K. and Dudek, F. E. (1988). The effects of the excitatory amino acid antagonist kynurenic acid on synaptic transmission to supraoptic neuroendocrine cells. Brain research, 442, 152-156. Giulian, D., Vaca K., Noonan, C. A. (1990). Secretion of neurotoxins by mononuclear phagocytes infected with HIV-1. Science, 250, 1593-1596. Haley, J. E., Sullivan, A. F., Dickenson, A. H. (1990). Evidence for spinal N-methyl-D- aspartate receptor involvement in prolonged chemical nociception in the rat. Brain research, 518, 218-226. Hansen, A. J., Lauritzen, M. and Wieloch, T. (1988). NMDA antagonists inhibit cortical spreading depression, but not anoxic depolarization. In Frontiers in excitatory amino acid research (eds. E. A. Cavalheiro, J. Lehmann, L. Turski) A. R. Liss, New York, pp. 661-666 Harrison, P. J., McLaughlin, D., Kerwin, R. W. (1991). Decreased hippocampal expression of a glutamate receptor gene in schizophrenia. Lancet, 337, 450-452. Hayashi, T.A. (1954). Effects of sodium glutamate on the nervous system. Keio journal of medicine 3, 183-192. Henderson, G., Johnson, J. W., Ascher, P. (1990). Competitive antagonists and partial agonists at the glycine modulatory site of the mouse N-methyl-D-aspartate receptor. Journal of physiology, 430, 189-212. Herberg, L. J., Rose, J. C. (1990). Effects of D-cycloserine and cycloleucine, ligands for the NMDA-associated strychnine- insensitive glycine site, on brain-stimulation reward and spontaneous locomotion. Pharmacology, biochemistry and behavior, 36, 735-738. Herrling, P. L. (1985). Pharmacology of the corticocaudate excitatory postsynaptic potential in the cat: evidence for its mediation by quisqualate- or kainate-receptors. Neuroscience, 14, 417-426. Herrling, P. L. and Hull, C. D. (1980). Iontophoretically applied dopamine depolarizes and hyperpolarizes the membrane of cat caudate neurons. Brain research, 192, 441-462. Herrling, P. L., Morris, R. and Salt, T. E. (1983). Effects of excitatory amino acids and their antagonists on membrane and action potentials of cat caudate neurones. Journal of physiology, 339, 207-222. Heyes, M. P., Brew, B. J., Martin, A., Price, R. W., Salazar, A. M., Sidtis, J. J., Yergey, J. J., Mouradian, M. M., Sadler, A. E., Keilp, J., Rubinow, D., and Markey, S. P. (1991). Quinolinic acid in cerebrospinal fluid and serum in HIV-1 infection: relastionship to clinical and neurological status. Annals of neurology, 29, 202-209. Honor , T. (1989). Excitatory amino acid receptor subtypes and specific antagonists. Medicinal research reviews, 9, 1-23. Hood, W. F., Compton, R. P., Monahan, J. B. (1989). D-Cycloserine: a ligand for the N- methyl-D-aspartate coupled glycine receptor has partial agonist characteristics. Neuroscience letters, 98, 91-95. Imperato, A., Scrocco,M. G., Bacchi, S., and Angelucci, L. (1990). NMDA receptors and in vivo dopamine release in the nucleus accumbens and caudatus. European journal of pharmacology, 187, 555-556. Jensen, L. H. and Sheardown, M. (1988). Lack of potent antiepileptic effect of specific non-NMDA EAA receptor antagonist. In Frontiers in excitatory amino acid research (eds. E. A. Cavalheiro, J. Lehmann and L. Turski) A. R. Liss, New York, pp. 219-226. Johnson, J., Ascher, P. (1987). Glycine potentiates the NMDA response in cultured mouse brain neurons. Nature, 325, 529-531. Katayama, Y., Becker, D. P., Tamura, T., Hovda, D. A. (1990). Massive increase in extracellular potassium and the indiscriminate release of glutamate following concussive brain injury. Journal of Neurosurgery, 73, 889-900. Kehne, J. H., McCloskey, T. C., Baron, B. M., Chi, E. M., Harrison, B. L., Whitten, J. P., Palfreyman, M. G. (1991): NMDA receptor complex antagonists have potential anxiolytic effects as measured with separation-induced ultrasonic vocalizations. European journal of pharmacology, 193, 283-292. Kemp, J. A. and Sillito, A. M. (1983). The nature of the excitatory transmitter mediating X and Y cells inputs to the cat dorsal lateral geniculate nucleus. Journal of physiology, 323, 377-391. Khanna, J. M., Wu, P. H., Weiner, J., Kalant, H. (1991). NMDA antagonists inhibits rapid tolerance to ethanol. Brain research bulletin, 26, 643-645. Kjellmer, I. (1991). Mechanisms of perinatal brain damage. Annals of medicine, 23, 675- 679. Klepstad, P., Maurset, A., Moberg, E. R., Oye, I. (1990). Evidence of a role for NMDA receptors in pain perception. European journal of pharmacology, 187, 513-518. Kleinschmidt,A., Bear,M.F. and Singer,W. (1987). Blockade of "NMDA" receptors disrupts experience-dependent plasticity of kitten striate cortex. Science, 238, 355-358. Klockgether, T., Turski, L. (1990). NMDA antagonists potentiate antiparkinsonian actions of L-Dopa in monoamine-depleted rats. Annals of neurology, 25, 539-546. Koh, J., Yang, L. L., Cotman, C. W. (1990). -Amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage. Brain research, 533, 315-320. Laborit, H., Huguenard, P., and Alluaume, R. (1952). Un nouveau stabilisateur v g tatif (le 4560 RP). La presse m dicale, 60, 206-208. Lauritzen, M. (1988). Cortical spreading depression: a putative migraine mechanism. Trends in neurosciences, 10, 8-12. Liebman, J. M. and Bennett, D. A. (1988). Anxiolytic actions of competitive N-methyl-D-aspartate receptor antagonists: a comparison with benzodiazepine modulators and dissociative anesthetics. In Frontiers in excitatory amino acid research (eds. E. A. Cavalheiro, J. Lehmann and L. Turski) A. R. Liss, New York, pp. 301-308. Liljequist, S. (1991). The competitive NMDA receptor antagonist, CGP 39551, inhibits ethanol withdrawal seizures. European Journal of Pharmacology, 192, 197-198. Liu, D., Thangnipon, W., McAdoo, D. J. (1991). Excitatory amino acids rise to toxic levels upon impact injury to the rat spinal cord. Brain research, 547, 344-348. Lodge, D., Aram, J. A., Church, J., Davies, S. N., Martin, D., Millar, J. and Zeman, S. (1988). Sigma opiates and excitatory amino acids. In Excitatory amino acids in health and disease (ed. D. Lodge) J. Wiley and Sons, New York, pp. 237-259. Lopez, F.J., Donoso, A. O., Negro-Vilar, A. (1990). Endogenous excitatory amino acid neurotransmission regulates the estradiol- induced LH surge in ovarieectomized rats. Endocrinology, 126, 1771-1773. Lucas, D. R. and Newhouse, J. P. (1957). The toxic effect of sodium-L-glutamate on the inner layers of the retina. Archives of ophtalmology 58, 193-204. Man, E. H., Sandhouse, M. E., Burg J. and Fisher G.H. (1983). Accumulation of D-aspartic acid with age in the human brain. Science, 220, 1407-1408. Mansbach, R. S. (1991). Effects of NMDA receptor ligands on sensorimotor gating in the rat. European journal of pharmacology, 202, 61-66. Maragos, W. F., Greenamyre, J. T., Penney, J. B. and Young, A. B. (1987). Glutamate dysfunction in Alzheimer's disease: an hypothesis. Trends in neurosciences, 65-68. Marranes, R., Willems, R., De Prins, E. and Wauquier, A. (1988). Evidence for a role of the N-methyl-D-aspartate (NMDA) receptor in cortical spreading depression in the rat. Brain research 457, 226-240. Mason, G. A., Bissette, G. and Nemeroff, C. B. (1983). Effects of excitotoxic amino acids on pituitary hormone secretion in the rat. Brain research, 289, 366-369. Meldrum, B., Wardley-Smit, B., Halsey, M. and Rostain, J.C. (1983). 2-Amino-phosphonoheptanoic acid protects against the high pressure neurological syndrome. European journal of pharmacology, 87, 501-502. Meldrum, B. (1985). Possible therapeutic applications of antagonists of excitatory amino acid neurotransmitters. Clinical science, 68, 113-122. Meldrum, B. (1986). Drugs acting on amino acid neurotransmitters. Advances in neurology, 43, 687-706. Meldrum, B. S. and Kerwin, R. W. (1987). Glutamate receptors and schizophrenia. Journal of psychopharmacology 1, 217-221. Meldrum, B.S. (1988). What are the future prospects for agents decreasing excitatory neurotransmission as anti-epileptic agents? In Frontiers in excitatory acid research (eds. E. A. Calvalheiro, J. Lehmann and L. Turski) A. R. Liss, New York, pp. 195-202. Miller, R. F. and Slaughter, M. M. (1986). Excitatory amino acid receptors of the retina: diversity of subtypes and conductance mechanisms. Trends in neurosciences, 9, 211- 218. Monahan, J. B., Handelmann, G. E., Hood, W. F., Cordi, A. A. D-cycloserine, a positive modulator of the N-methyl-D-aspartate receptor, enhances performance of learning tasks in rats. Pharmacology biochemistry and behavior, 34, 649-653. Mondadori, C., Ortmann, R., Petschke, F., Buerki, H., D'Amato, F., Meisburger, J. G. Fagg, G. E. (1988). In Frontiers in excitatory acid research (eds. E. A. Cavalheiro, J. Lehmann and L. Turski ) A. R. Liss, New York, pp. 419-426. Moroni, F., Lombardi, G., Carla, V., Pellegrini, D., Carassale, G. L. and Cortesini, C. (1986). Content of quinolinic acid and of other tryptophan metabolites increases in brain region of rats used as experimental models of hepatic encephalopathy. Journal of neurochemistry, 46, 869-874. Moroni,F., Luzzi,S., Franchi-Micheli,S., Zilletti,L. (1986). The presence of NMDA-type receptors for glutamic acid in the guinea pig myenteric plexus. Neuroscience letters, 68, 57-62. Morris, R. G. M., Anderson, E., Lynch, G. S. and Baudry, M. (1986). Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5. Nature, 319, 774-776. ye, V., Paulsen, O. and Maurset, A. (1992). Effects of ketamine on sensory perception: evidence for a role of N-methyl-D-aspartate receptors. The journal of pharmacology and experimental therapeutics, 260, 1209-1213. Ozyurt, E., Graham, D. I., Woodruff, G. N. and McCulloch, J. (1988). Protective Effect of the Glutamate Antagonist, MK-801 in Focal Cerebral Ischemia in the Cat. Journal of cerebral blood flow and metabolism, 8, 138-143. Palmer, A. M., Gershon, S. (1990). Is the neuronal basis of Alzheimer's disease cholinergic or glutamatergic? FASEB journal, 4, 2745-2752. Parada-Turska, J., Turski, W. A. (1990). Excitatory amino acid antagonists and memory: effect of drugs acting at N-methyl-D-aspartate receptors in learning and memory tasks. Neuropharmacology, 29, 1111-1116. Perry, T. L., Krieger, C., Hansen, S., Eisen, A. (1990). Amyotrophic lateral sclerosis: amino acid levels in plasma and cerebrospinal fluid. Annals of neurology, 28, 12-17. Plaitakis, A. (1990). Glutamate dysfunction and selective motor neuron degeneration in amyotrophic lateral sclerosis: a hypothesis. Annals of neurology, 28, 3-8. Rothman, S. M. (1984). Synaptic release of excitatory amino acid neurotransmitter mediates anoxic neuronal death. The journal of neuroscience 4, 1884-1891. Rothman, S. M. and Olney, J. W. (1987). Excitotoxicity and the NMDA receptor. Trends in neurosciences, 10, 299-301. Rothstein , J. D., Tsai, G., Kuncl, R. W., Clawson, L., Cornblath, D. R., Drachman, D. B., Pestronk, A., Stauch, B. L., Coyle, J. T. (1990). Abnormal excitatory amino acid metabolism in amyotrophic lateral sclerosis. Annals of neurology, 28, 18- 25. Rothstein, J. D., Martin, L. J., and Kuncl, R. W. (1992). Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis. The new England journal of medicine, 326, 1464-1468. Salt, T. E. (1987). Excitatory amino acid receptors and synaptic transmission in the rat ventrobasal thalamus. Journal of physiology, 391, 499-510. Salt, T. E., Eaton, S. A. (1990). Postsynaptic potentials evoked in ventrobasal thalamus neurones by natural sensory stimuli. Neuroscience letters, 114, 295-299. Salt, T. E. (1992). The possible involvement of excitatory amino acids and NMDA receptors in thalamic pain mechanisms and central pain syndromes. APS journal, 1, 52- 54. Schwarcz, R., Speciale, C., Gramsbergen, J. B. P. and Turski, W. (1988a). Kynurenines in the mammalian brain. In Frontiers in excitatory amino acid research (eds. E. A. Cavalheiro, J. Lehmann and L. Turski) A. R. Liss, New York, pp. 613-620. Schwarcz, R., Whetsell, W. O. and Mangano, R. M. (1983). Quinolinic acid: an endogenous metabolite that produces axon-sparing lesions in rat brain. Science, 219, 316-318. Schwarcz, R., Whetsell, W. O., Turski, W. A. (1988b). Kynurenines and nerve cell death. Neurodegenerative disorders, 7-19. Serrano, A., D'Angio, M., Scatton, B. (1989). NMDA antagonists block restraint-induced increase in extracellular DOPAC in rat nucleus accumbens. European journal of pharmacology, 162, 157-166. Simon, R. P., Swan, J. H., Griffith, T. and Meldrum, B. S. (1984). Blockade of N-methyl- D-aspartate receptors may protect against ischemic damage in the brain. Science, 226, 850-852. Sherman, A. D., Hegwood, T. S., Baruah, S., Waziri, R. (1991). Deficient NMDA-mediated glutamate release from synaptosomes of schizophrenics. Biological psychiatry, 30, 1191-1198. Spencer, P. S., Hugon, J., Ludolph, A., Nunn, P. B, Ross, S. M., Roy, D. N. and Schaumburg H.H. (1987a). Discovery and partial characterization of primate motor-system toxins. In Ciba Foundation Symposium 126: Selective Neuronal Death, Wiley and Sons, New York. pp. 221-238. Spencer, P. S., Nunn, P. B., Hugon, J., Ludolph, A. C., Ross, S. M., Roy, D. N. and Robertson,R.C. (1987b). Guam amyotrophic lateral sclerosis-parkinsonism-dementia linked to a plant excitant neurotoxin. Science, 237, 517-522. Stephens, D. N. and Andrews, J. S. (1988). N-methyl-D-aspartate antagonists in animal models of anxiety. In Frontiers in excitatory amino acid research (eds. E. A. Cavalheiro, J. Lehmann, and L. Turski) A. R. Liss, New York, pp. 309-316. Stone, T. W., Connick, J. H., Winn, P., Hastings, M. H. and English, M. (1987). Endoge nous excitotoxic agents. In Ciba Foundation Symposium 126: Selective Neuronal Death, Wiley and Sons, New York. pp. 204-220. Svensson, A., Pileblad, E., Carlsson, M. (1991). A comparison between the non-competitive NMDA antagonist dizocilpine (MK-801) and the competitive NMDA antagonist D-CPP-ene with regard to dopamine turnover and locomotor-stimulatory properties in mice. Journal of neural transmission [Gensect] 85, 117-129. Tang, A. H. and Ho, P. M. (1988). Both competitive and non- competitive antagonists of N-methyl-D-aspartic acid disrupt brightness discrimination in rats. European journal of pharmacology, 151, 143-146. The Scientist (1989). February 20, 14. Thomson, A.M. (1990). Glycine is a coagonist at the NMDA receptor/channel complex. Progress in Neurobiology, 35, 53-74. Thompson, L. T., Moskai, J. R., Disterhoft, J. F. (1992). Hippocampus-dependent learning facilitated by a monoclonal antibody or D-cycloserine. Nature, 359, 638-641. Troupin, A. S., Mendius, J. R., Cheng, F. and Risinger, M. W. (1986). MK-801. In New anticonvulsant drugs (eds. B. S. Meldrum and R. J. Porter) J. Libbey, London, pp. 191- 201. Trujillo, K. A., Akil, H. (1991). Inhibition of morphine tolerance and dependence by the NMDA receptor antagonist MK-801. Science, 251, 85-87. Trullas, R., Jackson, B., Skolnick, P. (1989). Anxiolytic properties of 1-aminocyclo-propane-carboxylic acid, a ligand at strychnine-insensitive glycine receptors. Pharmacology biochemistry and behavior, 34, 313-316. Turski, L., Klockgether, T., Sontag, KH, Herrling, P. L. and Watkins, J. C. (1987). Muscle relaxant and anticonvulsant activity of 3-(+-)-2-carboxy-piperazine-4-yl)propyl- l-phosphonic acid, a novel N-methyl-D-aspartate antagonist, in rodent. Neuroscience letters, 73, 143-148. Turski, L., Klockgether, T., Turski, W. A., Ikonomidou, C., Schwarz, M. and Sontag, K. H. (1988). Muscle relaxant action of excitatory amino acid antagonists: sites of action. In Frontiers in excitatory amino acid research (eds. E. A. Cavalheiro, J. Lehmann, L. Turski) A. R. Liss, New York, pp. 343-350. Turski, L., Bressler, K., Rettig, K.-J., Loeschmann, P.-A., Wachtel, H. (1991). Protection of substantia nigra from MPP+ neurotoxicity by N-methyl-D-aspartate antagonists. Nature, 349, 414-418. Turski, L., Stephens, D. N. (1992). Excitatory amino acid antagonists protect mice against MPP+ seizures. Synapse 10, 120-125. Urbanski, H. F., Ojeda, S. R. (1990). A role for N-methyl-D- aspartate (NMDA) receptors in the control of LH secretion and initiation of female puberty. Endocrinology, 126, 1774-1776. Valverius, P., Crabbe, J. C., Hoffmann, P. L., Tabakoff, B. (1990). NMDA receptors in mice bred to be prone or resistant to ethanol withdrawal seizures. European journal of pharmacology, 184, 185-189. Van den Pol, A. N., Wuarin, J.-P., Dudek, F. E. (1990). Glutamate, the dominant excitatory transmitter in neuroendocrine regulation. Science, 250, 1276-1278. Watkins, J. C. (1988). Thirty years of excitatory amino acid research. In Frontiers in excitatory amino acid research (eds. E. A. Cavalheiro, J. Lehmann and L. Turski). pp. 3-10. Whetsell, W. O., Koehler, C. and Schwarcz, R. (1988). Quinolinic acid: a glia-derived exitotoxin in the mammalian central nervous system. In the Biochemical pathology of astrocytes A.R. Liss, New York, pp.191-202. Wiley, J. W., Lu, Y., Owyang, C. (1991). Evidence for a glutamatergic neural pathway in the myenteric plexus. American journal of physiology and gastroenterology, 261, G693- G700. Woodruff, G. N., Foster, A. C., Wong, E. H .F., Gill, R., Kemp, J. A. and Iversen, L. L. (1988). Excitatory amino acids and neurodegenerative disorders: possible therapeutic indications. In Excitatory amino acids in health an disease (ed. D. Lodge) J. Wiley and Sons, pp. 379-389. Young, R. S. K., Petroff, O. A. C., Novotny, E. J., Wong, M. (1990). Neonatal excitotoxic brain research. Development Neuroscience, 12, 210-220. == end of als 18-B ==